I was having the same problem and Lee helped me figure it out..
This is for Windows PC,
When browsing files, if you have the Windows Preview Pane running and preview an audio file Windows 10 now opens a pop up, to play the audio.
That popup is what is interfering with GameGuru.
To fix this turn the Preview Pane off In the View Menu of Windows file explorer.
After doing this I stopped having issues.
"The cave you fear to enter, holds the treasure you seek." - Joseph Campbell
ASUS ROG G20- Desktop Intel Core i7-6700 -3.4Ghz - 16GB Memory - NVIDIA GeForce GTX 970-4GB - Windows 10 64bit